TY - JOUR A1 - Altmann, Thomas A1 - Müssig, Carsten T1 - Brassinosteroid signaling in plants Y1 - 2001 ER - TY - JOUR A1 - Altmann, Thomas A1 - Müssig, Carsten A1 - Fischer, Sabine T1 - Brassinosteroid-regulated gene expression Y1 - 2002 ER - TY - JOUR A1 - Altmann, Thomas A1 - Schlüter, U. A1 - Köpke, D. A1 - Müssig, Carsten T1 - Analysis of carbohydrate metabolism of CPD antisense plants and the brassinosteroid-deficient cbb1 mutant Y1 - 2002 ER - TY - JOUR A1 - Altmann, Thomas A1 - Törjek, Otto A1 - Berger, Dieter A1 - Meyer, Rhonda C. A1 - Müssig, Carsten A1 - Schmidt, K. J. A1 - Sorensen, T. R. A1 - Weisshaar, Bernd A1 - Olds-Mitchell, T. T1 - Establishment of a high-efficiency SNP-based framework marker set for Arabidopsis Y1 - 2003 ER - TY - JOUR A1 - Goll-Garcia, D. A1 - Mazuch, J. A1 - Altmann, Thomas A1 - Müssig, Carsten T1 - Exordium regulates brassinosteroid-responsive genes N2 - In a screen for potential mediators of brassinosteroid (BR) effects, the EXORDIUM (EXO) protein was identified as a regulator of BR-responsive genes. The EXO gene was characterized as a BR-up-regulated gene. EXO overexpression under the control of the 35SCaMV promoter resulted in increased transcript levels of the BR-up-regulated KCS1, Exp5, delta-TIP, and AGP4 genes, which likely are involved in the mediation of BR-promoted growth. 35S::EXO lines grown in soil or in synthetic medium showed increased vegetative growth in comparison to wild-type plants, resembling the growth phenotype of BR-treated plants. Thus, the EXO protein most likely promotes growth via the modulation of gene expression patterns. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved Y1 - 2004 ER - TY - JOUR A1 - Lisso, Janina A1 - Altmann, Thomas A1 - Müssig, Carsten T1 - Metabolic changes in fruits of the tomato d(x) mutant JF - Phytochemistry : an international journal of plant biochemistry KW - Solanum lycopersicum KW - Solanaceae KW - tomato KW - brassinosteroid KW - primary metabolism KW - fruit Y1 - 2006 U6 - https://doi.org/10.1016/j.phytochem.2006.07.008 SN - 0031-9422 VL - 67 IS - 20 SP - 2232 EP - 2238 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Lisso, Janina A1 - Altmann, Thomas A1 - Müssig, Carsten T1 - The AtNFXL1 gene encodes a NF-X1 type zinc finger protein required for growth under salt stress JF - FEBS letters : the journal for rapid publication of short reports in molecular biosciences N2 - The human NF-X1 protein and homologous proteins in eukaryotes represent a class of transcription factors which are characterised. by NF-X1 type zinc finger motifs. The Arabidopsis genome encodes two NF-X1 homologs, which we termed AtNFXL1 and AtNFXL2. Growth and survival was impaired in atnfxl1 knock-out mutants and AtNFXL1-antisense plants under salt stress in comparison to wild-type plants. In contrast, 35S: :AtNFXL1 plants showed higher survival rates. The AtNFXL2 protein potentially plays an antagonistic role. The Arabidopsis NF-X1 type zinc finger proteins likely are part of regulatory mechanisms, which protect major processes such as photosynthesis. KW - Arabidopsis thaliana KW - NF-X1 KW - salt stress Y1 - 2006 U6 - https://doi.org/10.1016/j.febslet.2006.07.079 SN - 0014-5793 VL - 580 IS - 22 SP - 4851 EP - 4856 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Lisso, Janina A1 - Schröder, Florian A1 - Müssig, Carsten T1 - EXO modifies sucrose and trehalose responses and connects the extracellular carbon status to growth JF - Frontiers in plant science N2 - Plants have the capacity to adapt growth to changing environmental conditions. This implies the modulation of metabolism according to the availability of carbon (C). Particular interest in the response to the C availability is based on the increasing atmospheric levels of CO2. Several regulatory pathways that link the C status to growth have emerged. The extracellular EXO protein is essential for cell expansion and promotes shoot and root growth. Homologous proteins were identified in evolutionarily distant green plants. We show here that the EXO protein connects growth with C responses. The exo mutant displayed altered responses to exogenous sucrose supplemented to the growth medium. Impaired growth of the mutant in synthetic medium was associated with the accumulation of starch and anthocyanins, altered expression of sugar-responsive genes, and increased abscisic acid levels. Thus, EXO modulates several responses related to the C availability. Growth retardation on medium supplemented with 2-deoxy-glucose, mannose, and palatinose was similar to the wildtype. Trehalose feeding stimulated root growth and shoot biomass production of exoplants where as it inhibited growth of the wildtype. The phenotypic features of the exo mutant suggest that apoplastic processes coordinate growth and C responses. KW - EXO KW - growth KW - sugar response KW - trehalose KW - apoplast Y1 - 2013 U6 - https://doi.org/10.3389/fpls.2013.00219 SN - 1664-462X VL - 4 IS - 25 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Lisso, Janina A1 - Steinhaeuser, Dirk A1 - Altmann, Thomas A1 - Kopka, Joachim A1 - Müssig, Carsten T1 - Identification of brassinosteroid-related genes by means of transcript co-response analyses N2 - The comprehensive systems-biology database (CSB.DB) was used to reveal brassinosteroid (BR)-related genes from expression profiles based on co-response analyses. Genes exhibiting simultaneous changes in transcript levels are candidates of common transcriptional regulation. Combining numerous different experiments in data matrices allows ruling out outliers and conditional changes of transcript levels. CSB.DB was queried for transcriptional co-responses with the BR-signalling components BRI1 and BAK1: 301 out of 9694 genes represented in the nasc0271 database showed co-responses with both genes. As expected, these genes comprised pathway-involved genes (e.g. 72 BR-induced genes), because the BRI1 and BAK1 proteins are required for BR-responses. But transcript co-response takes the analysis a step further compared with direct approaches because BR-related non BR-responsive genes were identified. Insights into networks and the functional context of genes are provided, because factors determining expression patterns are reflected in correlations. Our findings demonstrate that transcript co-response analysis presents a valuable resource to uncover common regulatory patterns of genes. Different data matrices in CSB.DB allow examination of specific biological questions. All matrices are publicly available through CSB.DB. This work presents one possible roadmap to use the CSB.DB resources Y1 - 2005 SN - 0305-1048 ER - TY - JOUR A1 - Meyer, Rhonda C. A1 - Müssig, Carsten A1 - Altmann, Thomas T1 - Genetic Diversity : Creation of novel genetic variants of arabidopsis Y1 - 2004 SN - 3-00-011587-0 ER -