@article{ColangeliSchlaegelOberteggeretal.2019,
  author    = {Colangeli, Pierluigi and Schl{\"a}gel, Ulrike E. and Obertegger, Ulrike and Petermann, Jana S. and Tiedemann, Ralph and Weithoff, Guntram},
  title     = {Negative phototactic response to UVR in three cosmopolitan rotifers: a video analysis approach},
  series = {Hydrobiologia : acta hydrobiologica, hydrographica, limnologica et protistologica},
  volume    = {844},
  journal   = {Hydrobiologia : acta hydrobiologica, hydrographica, limnologica et protistologica},
  number    = {1},
  publisher = {Springer},
  address   = {Dordrecht},
  issn      = {0018-8158},
  doi       = {10.1007/s10750-018-3801-y},
  pages     = {43 -- 54},
  year      = {2019},
  language  = {en}
}
@article{RomeroMujalliJeltschTiedemann2019,
  author    = {Romero-Mujalli, Daniel and Jeltsch, Florian and Tiedemann, Ralph},
  title     = {Elevated mutation rates are unlikely to evolve in sexual species, not even under rapid environmental change},
  series = {BMC Evolutionary Biology},
  volume    = {19},
  journal   = {BMC Evolutionary Biology},
  publisher = {BioMed Central},
  address   = {London},
  issn      = {1471-2148},
  doi       = {10.1186/s12862-019-1494-0},
  pages     = {9},
  year      = {2019},
  abstract  = {Background Organisms are expected to respond to changing environmental conditions through local adaptation, range shift or local extinction. The process of local adaptation can occur by genetic changes or phenotypic plasticity, and becomes especially relevant when dispersal abilities or possibilities are somehow constrained. For genetic changes to occur, mutations are the ultimate source of variation and the mutation rate in terms of a mutator locus can be subject to evolutionary change. Recent findings suggest that the evolution of the mutation rate in a sexual species can advance invasion speed and promote adaptation to novel environmental conditions. Following this idea, this work uses an individual-based model approach to investigate if the mutation rate can also evolve in a sexual species experiencing different conditions of directional climate change, under different scenarios of colored stochastic environmental noise, probability of recombination and of beneficial mutations. The color of the noise mimicked investigating the evolutionary dynamics of the mutation rate in different habitats. Results The results suggest that the mutation rate in a sexual species experiencing directional climate change scenarios can evolve and reach relatively high values mainly under conditions of complete linkage of the mutator locus and the adaptation locus. In contrast, when they are unlinked, the mutation rate can slightly increase only under scenarios where at least 50\% of arising mutations are beneficial and the rate of environmental change is relatively fast. This result is robust under different scenarios of stochastic environmental noise, which supports the observation of no systematic variation in the mutation rate among organisms experiencing different habitats. Conclusions Given that 50\% beneficial mutations may be an unrealistic assumption, and that recombination is ubiquitous in sexual species, the evolution of an elevated mutation rate in a sexual species experiencing directional climate change might be rather unlikely. Furthermore, when the percentage of beneficial mutations and the population size are small, sexual species (especially multicellular ones) producing few offspring may be expected to react to changing environments not by adaptive genetic change, but mainly through plasticity. Without the ability for a plastic response, such species may become - at least locally - extinct.},
  language  = {en}
}
@article{DeCahsanWestburyDrewsetal.2019,
  author    = {De Cahsan, Binia and Westbury, Michael V. and Drews, Hauke and Tiedemann, Ralph},
  title     = {The complete mitochondrial genome of a European fire-bellied toad (Bombina bombina) from Germany},
  series = {Mitochondrial DNA Part B},
  volume    = {4},
  journal   = {Mitochondrial DNA Part B},
  number    = {1},
  publisher = {Taylor \& Francis Group},
  address   = {London},
  issn      = {2380-2359},
  doi       = {10.1080/23802359.2018.1547143},
  pages     = {498 -- 500},
  year      = {2019},
  abstract  = {The European fire-bellied toad, Bombina bombina, is a small aquatic toad belonging to the family Bombinatoridae. The species is native to the lowlands of Central and Eastern Europe, where population numbers have been in decline in recent past decades. Here, we present the first complete mitochondrial genome of the endangered European fire-bellied toad from Northern Germany recovered using iterative mapping. Phylogenetic analyses including other representatives of the Bombinatoridae placed our German specimen as sister to a Polish B. bombina sequence with high support. This finding is congruent with the postulated Pleistocene history of the species. Our complete mitochondrial genome represents an important resource for further population analysis of the European fire-bellied toad, especially those found within Germany.},
  language  = {en}
}
@misc{DeCahsanWestburyDrewsetal.2019,
  author    = {De Cahsan, Binia and Westbury, Michael V. and Drews, Hauke and Tiedemann, Ralph},
  title     = {The complete mitochondrial genome of a European fire-bellied toad (Bombina bombina) from Germany},
  series = {Postprints der Universit{\"a}t Potsdam Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam Mathematisch-Naturwissenschaftliche Reihe},
  number    = {532},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-42322},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-423222},
  pages     = {3},
  year      = {2019},
  abstract  = {The European fire-bellied toad, Bombina bombina, is a small aquatic toad belonging to the family Bombinatoridae. The species is native to the lowlands of Central and Eastern Europe, where population numbers have been in decline in recent past decades. Here, we present the first complete mitochondrial genome of the endangered European fire-bellied toad from Northern Germany recovered using iterative mapping. Phylogenetic analyses including other representatives of the Bombinatoridae placed our German specimen as sister to a Polish B. bombina sequence with high support. This finding is congruent with the postulated Pleistocene history of the species. Our complete mitochondrial genome represents an important resource for further population analysis of the European fire-bellied toad, especially those found within Germany.},
  language  = {en}
}
@misc{RomeroMujalliJeltschTiedemann2019,
  author    = {Romero-Mujalli, Daniel and Jeltsch, Florian and Tiedemann, Ralph},
  title     = {Elevated mutation rates are unlikely to evolve in sexual species, not even under rapid environmental change},
  series = {Postprints der Universit{\"a}t Potsdam Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam Mathematisch-Naturwissenschaftliche Reihe},
  number    = {776},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-43905},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-439058},
  pages     = {11},
  year      = {2019},
  abstract  = {Background Organisms are expected to respond to changing environmental conditions through local adaptation, range shift or local extinction. The process of local adaptation can occur by genetic changes or phenotypic plasticity, and becomes especially relevant when dispersal abilities or possibilities are somehow constrained. For genetic changes to occur, mutations are the ultimate source of variation and the mutation rate in terms of a mutator locus can be subject to evolutionary change. Recent findings suggest that the evolution of the mutation rate in a sexual species can advance invasion speed and promote adaptation to novel environmental conditions. Following this idea, this work uses an individual-based model approach to investigate if the mutation rate can also evolve in a sexual species experiencing different conditions of directional climate change, under different scenarios of colored stochastic environmental noise, probability of recombination and of beneficial mutations. The color of the noise mimicked investigating the evolutionary dynamics of the mutation rate in different habitats. Results The results suggest that the mutation rate in a sexual species experiencing directional climate change scenarios can evolve and reach relatively high values mainly under conditions of complete linkage of the mutator locus and the adaptation locus. In contrast, when they are unlinked, the mutation rate can slightly increase only under scenarios where at least 50\% of arising mutations are beneficial and the rate of environmental change is relatively fast. This result is robust under different scenarios of stochastic environmental noise, which supports the observation of no systematic variation in the mutation rate among organisms experiencing different habitats. Conclusions Given that 50\% beneficial mutations may be an unrealistic assumption, and that recombination is ubiquitous in sexual species, the evolution of an elevated mutation rate in a sexual species experiencing directional climate change might be rather unlikely. Furthermore, when the percentage of beneficial mutations and the population size are small, sexual species (especially multicellular ones) producing few offspring may be expected to react to changing environments not by adaptive genetic change, but mainly through plasticity. Without the ability for a plastic response, such species may become - at least locally - extinct.},
  language  = {en}
}
@misc{ParaskevopoulouDennisWeithoffetal.2019,
  author    = {Paraskevopoulou, Sofia and Dennis, Alice B. and Weithoff, Guntram and Hartmann, Stefanie and Tiedemann, Ralph},
  title     = {Within species expressed genetic variability and gene expression response to different temperatures in the rotifer Brachionus calyciflorus sensu stricto},
  series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  number    = {796},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-44105},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-441050},
  pages     = {23},
  year      = {2019},
  abstract  = {Genetic divergence is impacted by many factors, including phylogenetic history, gene flow, genetic drift, and divergent selection. Rotifers are an important component of aquatic ecosystems, and genetic variation is essential to their ongoing adaptive diversification and local adaptation. In addition to coding sequence divergence, variation in gene expression may relate to variable heat tolerance, and can impose ecological barriers within species. Temperature plays a significant role in aquatic ecosystems by affecting species abundance, spatio-temporal distribution, and habitat colonization. Recently described (formerly cryptic) species of the Brachionus calyciflorus complex exhibit different temperature tolerance both in natural and in laboratory studies, and show that B. calyciflorus sensu stricto (s.s.) is a thermotolerant species. Even within B. calyciflorus s.s., there is a tendency for further temperature specializations. Comparison of expressed genes allows us to assess the impact of stressors on both expression and sequence divergence among disparate populations within a single species. Here, we have used RNA-seq to explore expressed genetic diversity in B. calyciflorus s.s. in two mitochondrial DNA lineages with different phylogenetic histories and differences in thermotolerance. We identify a suite of candidate genes that may underlie local adaptation, with a particular focus on the response to sustained high or low temperatures. We do not find adaptive divergence in established candidate genes for thermal adaptation. Rather, we detect divergent selection among our two lineages in genes related to metabolism (lipid metabolism, metabolism of xenobiotics).},
  language  = {en}
}
@article{ParaskevopoulouDennisWeithoffetal.2019,
  author    = {Paraskevopoulou, Sofia and Dennis, Alice B. and Weithoff, Guntram and Hartmann, Stefanie and Tiedemann, Ralph},
  title     = {Within species expressed genetic variability and gene expression response to different temperatures in the rotifer Brachionus calyciflorus sensu stricto},
  series = {PLoS ONE},
  volume    = {9},
  journal   = {PLoS ONE},
  number    = {14},
  publisher = {PLoS ONE},
  address   = {San Francisco, California},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0223134},
  pages     = {21},
  year      = {2019},
  abstract  = {Genetic divergence is impacted by many factors, including phylogenetic history, gene flow, genetic drift, and divergent selection. Rotifers are an important component of aquatic ecosystems, and genetic variation is essential to their ongoing adaptive diversification and local adaptation. In addition to coding sequence divergence, variation in gene expression may relate to variable heat tolerance, and can impose ecological barriers within species. Temperature plays a significant role in aquatic ecosystems by affecting species abundance, spatio-temporal distribution, and habitat colonization. Recently described (formerly cryptic) species of the Brachionus calyciflorus complex exhibit different temperature tolerance both in natural and in laboratory studies, and show that B. calyciflorus sensu stricto (s.s.) is a thermotolerant species. Even within B. calyciflorus s.s., there is a tendency for further temperature specializations. Comparison of expressed genes allows us to assess the impact of stressors on both expression and sequence divergence among disparate populations within a single species. Here, we have used RNA-seq to explore expressed genetic diversity in B. calyciflorus s.s. in two mitochondrial DNA lineages with different phylogenetic histories and differences in thermotolerance. We identify a suite of candidate genes that may underlie local adaptation, with a particular focus on the response to sustained high or low temperatures. We do not find adaptive divergence in established candidate genes for thermal adaptation. Rather, we detect divergent selection among our two lineages in genes related to metabolism (lipid metabolism, metabolism of xenobiotics).},
  language  = {en}
}