@article{YenesewInduliDereseetal.2004,
  author    = {Yenesew, Abiy and Induli, M. and Derese, Solomon and Midiwo, Jacob O. and Heydenreich, Matthias and Peter, Martin G. and Akala, Hoseah M. and Wangui, Julia and Liyala, Pamela and Waters, Norman C.},
  title     = {Anti-plasmodial flavonoids from the stem bark of Erythrina abyssinica},
  issn      = {0031-9422},
  year      = {2004},
  abstract  = {The ethyl acetate extract of the stem bark of Erythrina abyssinica showed anti-plasmodial activity against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum with IC50 values of 7.9 +/- 1.1 and 5.3 +/- 0.7 mug/ml, respectively. From this extract, a new chalcone, 2,3,4,4'-tetrahydroxy-5- prenylchalcone (trivial name 5-prenylbutein) and a new flavanone, 4',7-dihydroxy-3'-methoxy-5'- prenylflavanone (trivial name, 5-deoxyabyssinin II) along with known flavonoids have been isolated as the anti- plasmodial principles. The structures were determined on the basis of spectroscopic evidence. (C) 2004 Elsevier Ltd. All rights reserved},
  language  = {en}
}