TY  - JOUR
A1  - Hentrich, Doreen
A1  - Tauer, Klaus
A1  - Espanol, Montserrat
A1  - Ginebra, Maria-Pau
A1  - Taubert, Andreas
T1  - EDTA and NTA effectively tune the mineralization of calcium phosphate from bulk aqueous solution
T2  - Biomimetics
N2  - This study describes the effects of nitrilotriacetic acid (NTA) and ethylenediaminotetraacetic acid (EDTA) on themineralization of calciumphosphate from bulk aqueous solution. Mineralization was performed between pH 6 and 9 and with NTA or EDTA concentrations of 0, 5, 10, and 15 mM. X-ray diffraction and infrared spectroscopy show that at low pH, mainly brushite precipitates and at higher pH, mostly hydroxyapatite forms. Both additives alter the morphology of the precipitates. Without additive, brushite precipitates as large plates. With NTA, the morphology changes to an unusual rod-like shape. With EDTA, the edges of the particles are rounded and disk-like particles form. Conductivity and pH measurements suggest that the final products form through several intermediate steps.
KW  - biomineralization
KW  - biomimetic mineralization
KW  - calcium phosphate
KW  - NTA
KW  - EDTA
KW  - precipitation
KW  - brushite
KW  - hydroxyapatite
Y1  - 2017
UR  - https://publishup.uni-potsdam.de/frontdoor/index/index/docId/46917
SN  - 2313-7673
VL  - 2
IS  - 4
PB  - MDPI
CY  - Basel
ER  -